Scoring insertion-deletion polymorphisms by dynamic allele-specific hybridization
نویسندگان
چکیده
منابع مشابه
Forensic Identification by Using Insertion-deletion Polymorphisms
Forensic science is basically the determination of the human identity. With advances in science and technology and the availability of DNA profiling, it is possible now to determine the identity even in decomposed and mutilated bodies and even with parts of a body as trivial as a hair or a drop of a blood. Methods and materials: Short tandem repeat polymorphism (STRP) genotyping and single nucl...
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We report the identification and characterization of 2,000 human diallelic insertion/deletion polymorphisms (indels) distributed throughout the human genome. Candidate indels were identified by comparison of overlapping genomic or cDNA sequences. Average confirmation rate for indels with a > or =2-nt allele-length difference was 58%, but the confirmation rate for indels with a 1-nt length diffe...
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Genotyping of SNPs (single-nucleotide polymorphisms) has challenged the development of several novel techniques. Most of these methods have been introduced to discriminate binary SNPs in diploid species. In the present study, the quantitative genotyping of SNPs in natural DNA pools of a polyploid organism via DNA microarrays was analysed. Three randomly selected SNP loci were genotyped in the t...
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The European and African contribution to the pre-existing Native American background has influenced the complex genetic pool of Colombia. Because colonisation was not homogeneous in this country, current populations are, therefore, expected to have different proportions of Native American, European and African ancestral contributions. The aim of this work was to examine 11 urban admixed populat...
متن کاملA new multiplex for human identification using insertion/deletion polymorphisms.
Human identification is usually based on the study of STRs or SNPs depending on the particular characteristics of the investigation. However, other types of genetic variation such as insertion/deletion polymorphisms (indels) have considerable potential in the field of identification, since they can combine the desirable characteristics of both STRs and SNPs. In this study, a set of 38 non-codin...
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ژورنال
عنوان ژورنال: BioTechniques
سال: 2003
ISSN: 0736-6205,1940-9818
DOI: 10.2144/03352st01